Have recurrent or metastatic squamous cell carcinoma of the anal canal that cannot be surgically resected. Patients with HIV, HBV, and HCV are eligible
Patients are not eligible if they:
Have been previously treated with systemic chemotherapy or an investigational agent for the treatment of inoperable recurrent/metastatic disease
Have had prior treatment with immunotherapy
Have active autoimmune disease
Have history/evidence of interstitial lung disease
There are additional eligibility requirements for this study: see the complete list at clinicaltrials.gov. Contact your doctor if you are unsure of your eligibility. You can also contact a study doctor who will review the criteria with you and help determine your eligibility.