CORRECT-MRD II: Who is eligible to join?

Summarized inclusion and exclusion criteria are below. Please find full inclusion and exclusion criteria at

Patients are eligible to join if they:

  1. 18 years of age or older
  2. Diagnosis of pathologic Stage II or Stage III carcinoma of the colon or rectum
  3. Have undergone complete surgical resection of CRC, with last surgery occurring within 180 days prior to enrollment
  4. Healthy enough to participate
  5. Able to understand and provide written informed consent
  6. Willing and able to comply with the study requirements, which includes the collection of approximately 43mL of blood for each research blood draw (up to 15 total blood draws for the duration of the study)

Patients are ineligible to join the trial if they:

  • Initiated adjuvant (post-surgical) therapy for current CRC diagnosis. Note: prior neoadjuvant (done before surgery) therapy acceptable
  • Pregnant or breastfeeding at time of enrollment.
  • Prior history of any invasive cancer (including CRC) within the past 3 years prior to informed consent, with the exception of non-melanoma skin cancer. Patients with a prior history of noninvasive (in situ) carcinomas may participate after definitive treatment
  • Prior transplant history:
    • Prior allogeneic hematopoietic stem cell transplant at any time
    • Prior solid organ transplant within the last 2 years prior to enrollment.
  • Multiple cancer diagnoses: Synchronous or asynchronous diagnoses (or suspicion) of multiple primary cancers at the time of eligibility screening

There are additional eligibility requirements for this study: see the complete list at Contact your doctor if you are unsure of your eligibility.  You can also contact a study doctor who will review the criteria with you and help determine your eligibility.